Lab Members

  

  

  

Jeremy Van Raamsdonk, PhD, MSc

Principal Investigator

 


Current Members

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Zenith Rudich, PhD

Postdoctoral Fellow
Joined Sep. 2019

Projects: Identifying common downstream mediators of longevity in long-lived genetic mutants from different pathways of lifespan extension; Determining the extent to which these common downstream mediators of longevity are neuroprotective in models of Parkinson’s and Huntington’s disease.

Interests: Fitness and nutrition obsessed, with a splatter of painting for good measure.

E-mail: zenith.rudich@mail.mcgill.ca

See Paige on PubMed

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Shusen Zhu, MSc

Research Assistant and Lab Manager
Joined Jul. 2022

Projects: Investigating tissue-specific effects of sod-2 disruption on lifespan and stress resistance and the role of mitochondrial superoxide in nuo-6 lifespan by overexpression of sod-2.

Interests: Hiking, aliens, traveling, cooking.
 
E-mail: shusen.zhu@rimuhc.ca

See Shusen on PubMed

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Annika Traa

PhD Student
McGill, Integrated Program in Neuroscience
Joined Sep. 2019

Projects: Characterizing the role of mitochondrial dynamics in stress resistance and longevity; Identifying changes in mitochondrial morphology in models of Huntington's disease; Investigating the role of the DAF-16/FOXO stress response in long-lived reduced insulin signaling and mitochondrial mutants.

Interests: Hiking, good books, large amounts of coffee and trying to keep her plants alive.

E-mail: annika.traa@mail.mcgill.ca

See Annika on Google Scholar

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Alibek Moldakozhayev, MSc

PhD Student
McGill, Integrated Program in Neuroscience
Joined Jan. 2021

Projects: Studying an effect of aging on neuronal function.

Interests: Aging, Quantum physics, Astronomy, Robotics, Travel.

E-mail: alibek.moldakozhayev@mail.mcgill.ca

See Alibek on Google ScholarLearn more...

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Ulrich Anglas

PhD Student
McGill, Integrated Program in Neuroscience
Joined Sep. 2019

Projects: Investigating which mechanisms are involved in lifespan-extension of mutants that lack the ROS scavenger SOD-2. This is of interest since ROS have been associated with aging but it is not known precisely how.

Interests: rock-climbing, running, drawing and hiking. I also have an interest in mythology, movies and tv shows.

E-mail: ulrich.anglas@mail.mcgill.ca

See Ulrich on PubMed

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Bokang Ko

PhD student
McGill, Integrated Program in Neuroscience
Joined Sep. 2022

Projects: Investigating the relationship between the C. elegans innate immune pathway and the mitochondria, and how they are interconnected to the process of aging and their lifespan.

Interests: Hiking, drawing, addicted to coffee

E-mail: bokang.ko@mail.mcgill.ca


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Abdelrahman AlOkda, MSc

PhD Student
McGill, Integrated Program in Neuroscience
Joined Sep. 2021

Projects: Identifying common downstream mediators of neuroprotection in models of genetic and chemically induced neurodegeneration (i.e. PD, AD, HD and ALS). This will help with the developing/repurposing of pharmacologic treatments for neurodegenerative diseases.

Interests: MMORPG/MOBA games and anime.

E-mail: abdelrahman.alokda@mail.mcgill.ca

See Abdel on Google Scholar

Mobirise

 

 

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Suleima Jacob-Tomas, MSc

PhD Student
McGill, Integrated Program in Neuroscience
Joined: January 2023

Projects: Examining the molecular mechanisms by which mild impairment of mitochondrial function contributes to increased stress resistance, slow physiologic rates, and extended longevity.

Interests: Comic book and coffee enthusiast, who enjoys spending quality time with family, friends, good books, and her fur children.
 
E-mail: suleima.jacob@mail.mcgill.ca 

See Suleima on Google scholar


Lab Alumni

Graduate Students  and Postdoctoral Fellows



Allison Keil (April – June 2023). Allison joined the Van Raamsdonk lab for a research rotation as part of the IPN graduate program. She characterized novel worm models that overexpressed mitochondrial fission and fusion genes.


Sonja Soo (Sep 2019 - Jun 2022): Sonia obtained a PhD degree from McGill's IPN program. Her research at the Van Raamsdonk lab focused on identifying overlapping mechanisms of lifespan extension in long-lived mutants, involving evaluation of the 7 pillars of aging in each mutant. 


Juliane Campos was a postdoctoral fellow at Harvard Medical School (December 2020 - July 2022). Her projects examined the role of innate immunity in the extend longevity of the long-lived mitochondrial mutants and the relationship between exercise, mitochondrial dynamics and aging. Juliane’s work was published in PNAS and EMBO Reports.


Thomas Liontis (Sept 2018 - August 2020): Thomas obtained a Master's degree from McGill's IPN program. His research at the Van Raamsdonk lab focused on elucidating the conditions required for ROS-mediated lifespan extension and investigating mechanisms of stress resistance in mutants of mitochondrial dynamics.

Undergraduate Students

Alexa Di Pede (May-August 2023). Alexa was a summer student intern from McMaster University. Alexa was awarded an NSERC Undergraduate student research award (USRA) to examine the relationship between the mitochondrial unfolded protein response, lifespan and stress resistance. She determined the optimum levels and timing of expression of constitutively active ATFS-1 for lifespan and resilience.


Rebecca Li (Sept. 2022 – June 2023). Rebecca was a student intern from the CEGEP Marionopolis. Rebecca completed a research project examining the ability of a compound called cyrene to protect against neurodegenerative diseases. Rebecca presented her work at regional, provincial and national science and technology fairs. She placed 1st in the Quebec provincial science fair and won a silver medal at the Canadian national science fair.


Namasthée Harris-Gauthier (2019-2020): Namasthée did an 8 month undergraduate project with the Van Raamsdonk lab, focusing on the involvement of the thioredoxin system on lifespan and resistance to stress.

Hazel Shields (Jan - Sep 2020): Hazel joined the lab at the beginning of the year for a 4 month undergraduate project during which she investigated how an impaired DAF-16/FOXO stress response affects lifespan and stress resistance of long-lived mitochondrial mutants. Starting in May, she then completed a 4 month NSERC USRA project in the lab, during which she focused on the effects of reactive oxygen species on aging across the tree of life.

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